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Why Zoladex is prescribed

The main aim when treating prostate cancer is to help men live as long as possible and help them to have an improvement to their current quality of life.

You have been prescribed Zoladex for the treatment of prostate cancer.

Zoladex is prescribed to help men with prostate cancer at different stages:

  • High-risk localised
  • Locally advanced
  • Metastatic

For men with high-risk localised prostate cancer1,2

  • Zoladex can be given before radiotherapy, where it has been shown to improve disease-free survival1-3
  • Zoladex can be given after radiotherapy where it has been shown to improve both disease-free survival and overall survival1-3

For men with locally advanced prostate cancer1,3

  • Zoladex can be given before or after radiotherapy in the same way as in localised prostate cancer1-3
  • Zoladex can be prescribed as an alternative to surgical castration. Used in this way, Zoladex has been shown to be as effective for survival as other therapies called anti-androgens1-3

For men with locally advanced prostate cancer at high risk of disease progression, Zoladex can be given at the same time as radical prostatectomy where it has been shown to improve disease-free survival.1,2

 

For men with metastatic prostate cancer1,2

  • Zoladex has shown to be similar at increasing survival as surgical castrations1,2

Survival - what it means

  • Disease-free survival is how long you live without any sign of the disease after treatment.
  • Overall survival is how long you live after treatment.

Reporting of side effects

Like all medicines, Zoladex can cause side effects, although not everybody gets them.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.

  1. Zoladex 10.8 mg SPC. https://www.medicines.org.uk/emc/medicine/8146. (Accessed July 2017).
  2. Zoladex 3.6 mg SPC. https://www.medicines.org.uk/emc/medicine/7855. (Accessed July 2017).
  3. Evans PE et al. BJU Int 2005;95: 743-749.

GB-6242. Date of Preparation: Sept 2017